Singapore Clinical Trial: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined ineligible for PD(L)1 therapy based on PD-L1 negative disease

Singapore, Aug. 7 -- The Health Sciences Authority received information related to the study titled 'A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy v... Read More

Clinical Trial: Evaluating the Intraoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block in Parturient Undergoing Elective Cesarean Section for Placenta Accreta Under General Anesthesia.

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07748741) titled 'Evaluating the Intraoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Blo... Read More

Singapore Clinical Trial: CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion

Singapore, Aug. 7 -- The Health Sciences Authority received information related to the study titled 'CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel... Read More

Clinical Trial: A Prospective, Multicenter, Single-Arm Clinical Trial of Thrombectomy Systems

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07749820) titled 'A Prospective, Multicenter, Single-Arm Clinical Trial of Thrombectomy Systems' on Aug. 03. ... Read More

Singapore Clinical Trial: A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus Adjuvant Chemotherapy Versus Placebo Plus Adjuvant Chemotherapy in Stage IB-IIIA NSCLC Patients with Uncommon EGFR Mutations Following Complete Tumor Resection (REZILIENT4)

Singapore, Aug. 7 -- The Health Sciences Authority received information related to the study titled 'A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus Adj... Read More

Singapore Clinical Trial: Beamion LUNG-3: A randomized, controlled, multi-center trial evaluating zongertinib as an adjuvant monotherapy compared with standard of care in patients with early-stage, resectable non-small cell lung cancer (Stage II-IIIB) harboring tyrosine kinase domain activating HER2 mutations

Singapore, Aug. 7 -- The Health Sciences Authority received information related to the study titled 'Beamion LUNG-3: A randomized, controlled, multi-center trial evaluating zongertinib as an adjuvant ... Read More

Clinical Trial: Testing the Impact of the Parenting Young Children Check-up

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07750054) titled 'Testing the Impact of the Parenting Young Children Check-up' on July 23. Brief Summary: The... Read More

Clinical Trial: Mobile Health Intervention to Increase Activity in Heart Failure Study

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07750262) titled 'Mobile Health Intervention to Increase Activity in Heart Failure Study' on July 25. Brief S... Read More

Clinical Trial: Enhancing Cognitive and Work/School Outcomes in First Episode Psychosis Using Cognitive Self-Management Strategies

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07749105) titled 'Enhancing Cognitive and Work/School Outcomes in First Episode Psychosis Using Cognitive Self... Read More

Singapore Clinical Trial: A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the effects of oral TRPC6 inhibitor BI 764198 taken over a 104 week treatment period in adult and adolescent participants with primary focal segmental glomerulosclerosis (pFSGS) or genetic FSGS related to TRPC6 gene variants

Singapore, Aug. 7 -- The Health Sciences Authority received information related to the study titled 'A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the eff... Read More

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